WHO Updates Essential Medicines List with Key Cancer and Diabetes Treatments

September 8, 2025

As a seasoned observer of global health trends, I can tell you that few updates hold as much weight as those from the World Health Organization’s Essential Medicines List (EML). This year, the WHO has once again demonstrated its commitment to global health equity, releasing a monumental update that specifically targets two of the most pervasive and challenging diseases of our time: cancer and diabetes. These additions aren’t just about new drugs.

Understanding the WHO Essential Medicines List (EML) Update

What is the WHO EML, and why is it Important?

For decades, the WHO Essential Medicines List (EML) has served as a bedrock for national health systems across the globe. It’s more than just a catalog; it’s a vital guide helping countries prioritize and procure the most impactful and cost-effective medicines. By identifying treatments considered essential for addressing the most prevalent health conditions, the EML directly influences national procurement strategies, supply chain management, and even reimbursement policies. Its power lies in its ability to drive global health equity, ensuring that foundational, safe, and effective treatments are available where they are needed most.

Key Highlights of the 24th EML and 10th EMLc Editions

The 24th edition of the EML and the 10th edition of the Essential Medicines List for Children (EMLc) bring forth updates that resonate deeply within the medical community. While the lists always reflect evolving scientific evidence, this particular update is distinguished by its focused and impactful additions in oncology and diabetology. These changes underscore the WHO’s adaptive approach to addressing global health burdens, recognizing that access to advanced treatments is crucial for improving patient outcomes worldwide.

Advancements in Cancer Treatment Accessibility

Introducing Immune Checkpoint Inhibitors

One of the most exciting developments in modern oncology has been the emergence of immune checkpoint inhibitors. These groundbreaking therapies work by essentially ‘unleashing’ the body’s own immune system to recognize and attack cancer cells. Their inclusion on the EML marks a pivotal moment, shifting advanced cancer care from being a luxury to an essential right for many.

Specific Cancer Drugs Added: Pembrolizumab, Atezolizumab, and Cemiplimab

The latest EML specifically includes PD-1/PD-L1 immune checkpoint inhibitors such as Pembrolizumab, Atezolizumab, and Cemiplimab. These powerful drugs have been added for critical indications, including metastatic cervical cancer, advanced colorectal cancer with specific genetic markers, and metastatic non-small cell lung cancer. This targeted inclusion aims to ensure that patients with these challenging cancers can access treatments that significantly improve their prognosis and quality of life.

WHO’s Criteria for Essential Cancer Therapies

The decision to include these complex and often expensive cancer therapies is not taken lightly. The WHO’s expert committee rigorously assesses each medicine based on robust evidence of efficacy and safety, along with a comprehensive evaluation of its cost-effectiveness, especially for low and middle-income countries. The goal is always to provide the greatest health benefit to the largest number of people, balancing clinical impact with the realities of global healthcare resources.

New Hope for Diabetes Management, Especially with Comorbidities

The Role of GLP-1 Receptor Agonists (Semaglutide, Dulaglutide, Liraglutide, Tirzepatide)

For individuals living with type 2 diabetes, particularly those with significant comorbidities like cardiovascular disease, chronic kidney disease, or obesity, the EML now offers new hope. GLP-1 receptor agonists such as Semaglutide, Dulaglutide, and Liraglutide, along with the dual GLP-1/GIP agonist Tirzepatide, have been added. These medications not only help control blood sugar but also offer vital protective benefits for the heart and kidneys, representing a paradigm shift in holistic diabetes management.

Rapid-Acting Insulin Analogues and Improved Diabetes Care

Beyond the GLP-1s, the EML also now features rapid-acting insulin analogues. These newer insulins offer more flexible dosing and better post-meal glucose control compared to older insulins, benefiting patients with type 1, type 2, and even gestational diabetes. Their inclusion underscores a commitment to providing patients with more effective tools to manage their condition and improve daily quality of life.

Addressing Access and Affordability Challenges for GLP-1s

While the inclusion of GLP-1s is a monumental step, the challenge of access and affordability remains, particularly in resource-limited settings. These medications can be expensive, and ensuring their widespread availability will require concerted efforts from governments, pharmaceutical companies, and global health organizations to negotiate prices and develop sustainable supply chains.

Broader Implications for Global Health Equity

Expanding Beyond Cancer and Diabetes: Cystic Fibrosis, Psoriasis, Haemophilia

The EML update’s impact isn’t confined solely to cancer and diabetes. The list now includes crucial therapies for other conditions, such as triple therapy for cystic fibrosis, biological agents for severe psoriasis, and innovative treatments for haemophilia. These additions highlight the WHO’s broad commitment to ensuring comprehensive access to care across a spectrum of diseases.

Environmental Considerations: Halothane Removal

In a forward-thinking move, the EML also saw the removal of halothane, an older anesthetic, primarily due to its significant environmental impact. This decision reflects a growing recognition within global health that medical practices must also consider their ecological footprint, promoting safer and more sustainable alternatives.

The EML as a Global Policy Tool

Ultimately, the EML serves as a powerful global policy tool. It not only guides procurement but also fosters innovation, encourages generic production, and sets a benchmark for what constitutes essential healthcare worldwide. Each update reinforces its role in shaping national health priorities and advocating for universal health coverage.

How Medstown Supports Access to Essential Medicines

Bridging the Gap: Medstown’s AI-Powered Delivery

Here at Medstown, we deeply understand the critical importance of timely access to essential medicines. That’s why we’ve built a robust platform for online medicine delivery, specifically designed to bridge the gap between updated lists like the WHO EML and the patients who need these treatments. Our innovative AI-powered delivery services ensure that authentic medicines are delivered promptly, directly to your doorstep. We are committed to revolutionizing medicine accessibility, especially for those crucial medications making their way onto the essential lists.

Your Trusted Partner for Timely Access in India

Medstown is dedicated to being your reliable partner for healthcare needs across India, with extensive coverage in Hyderabad and rapidly expanding regions. Our commitment means you can easily use our platform for easy prescription upload, connect with healthcare professionals through 24/7 teleconsultations, and receive genuine products sourced from a network of trusted local pharmacies. We prioritize swift delivery timeframes, aiming for 30-minute delivery to ensure that essential medicines reach you when they matter most. Should you have any questions or require assistance, our dedicated Medstown Support team is always ready to help.

Frequently Asked Questions (FAQs)

  • Q1: What is the WHO Essential Medicines List (EML)?
    A1: The WHO EML is a guide for countries to identify priority medicines for their health systems, ensuring access to safe and effective treatments for the most prevalent conditions. It influences procurement, supply, and reimbursement policies globally.
  • Q2: Which new cancer treatments have been added to the EML?
    A2: The latest update includes PD-1/PD-L1 immune checkpoint inhibitors like Pembrolizumab, Atezolizumab, and Cemiplimab, specifically for metastatic cervical, colorectal, and non-small cell lung cancers, aiming to enhance the body’s immune response against cancer.
  • Q3: What new diabetes medications are now on the EML?
    A3: For type 2 diabetes with comorbidities (cardiovascular disease, chronic kidney disease, obesity), GLP-1 receptor agonists (Semaglutide, Dulaglutide, Liraglutide) and the GLP-1/GIP dual agonist Tirzepatide were added. Rapid-acting insulin analogues are also new for type 1, type 2, and gestational diabetes.
  • Q4: How does Medstown help patients access these essential medicines?
    A4: Medstown leverages AI-powered delivery services and partnerships with trusted local pharmacies to provide 30-minute online medicine delivery of authentic medicines across Hyderabad and expanding regions in India. This ensures timely access to crucial treatments, including those on the updated WHO EML. For any queries, you can reach out to our Medstown Support team is always ready to help.

Stay informed about the latest health advancements and ensure you have access to the medicines you need. Visit Medstown today to experience our fast, reliable, and authentic medicine delivery services.


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